Combine yeast and warm water in a small bowl and let sit for 10 minutes.
Combine red velvet cake mix and 1 cup flour with a whisk. Once the yeast hasbloomed, mix it in with the red velvet mixture using a wooden spoon or benchscraper.
Add additional flour and knead by hand to form a soft dough.
Spray a large bowl with non-stick cooking spray and place dough inside.
Cover the bowl with plastic wrap and let the dough rest in a warm place for anhour until doubled in size.
Filling:
In a small bowl, mix brown sugar, cinnamon, and nutmeg set aside.
After the dough has risen place dough on a lightly floured surface and roll out into alarge rectangle about ¼ "thick.
Spread melted butter over the dough and sprinkle with brown sugar mixture.
Start from the farthest edge and carefully roll the dough into a log.
Using a sharp knife, cut into 12 equal pieces.
Place cinnamon rolls in a 9x13-inch baking dish with parchment paper.
Cover with a kitchen towel and let rise for another 1 hour.
Preheat the oven to 350°.
Bake 15-20 minutes or until lightly browned.
Topping:
In a small bowl, beat cream cheese and butter until fluffy.
Add powdered sugar and vanilla extract and mix until combined.